Those at high risk of colon cancer, for example, people with lynch syndrome,there is a history of heredity, or people who frequent contact with carcinogens can reduce risk by taking aspirin every day.
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This was evidenced by a study conducted in England by Sir John Burn of Newcastle University. He and his team studied 861 people with Lynch syndrome, a tendency to suffer from cancer due to heredity.
Every day Burn and his team gave the patients 600 mg of aspirin. He said at the end of the age of 40 or 50 years the cancer prevention benefits of aspirin is stronger when the patient began to eat them.
The study found that Among a group of people with what is known as Lynch syndrome who took daily aspirin for two years or more were 60 percent less likely to develop cancer of the rectum or colon than those not taking the drug.
People with Lynch syndrome are at higher risk for some other cancers — stomach, uterine, pancreatic . About 50 to 70 percent of people with Lynch syndrome develop colorectal cancer. making them a group in whom preventive measures can be more easily studied than the general population because the disease occurs earlier and progresses more rapidly.
In the new study, published in The Lancet, researchers randomly assigned 861 people in 16 countries who had Lynch syndrome to take two aspirin tablets a day or identical-looking placebos. After slightly more than two years, there was no difference between the two groups in cancer incidence.
But after about five years, there was a difference. Eighteen people taking aspirin developed cancer compared with 30 taking a placebo. Not every participant stayed with the program. When only those who took aspirin for two years or more were considered, the reduction in cancer rate was about 60 percent.
About 15 percent of cancers in the general population result from mutations in the genes affected in Lynch syndrome — a sort of DNA spell-checker known as “mismatch-repair.” Other studies, however, have shown that aspirin lowers the risk of colorectal cancer resulting from other mutations, too.
However, aspirin has side effects one of them is bleeding. “If we give all patients aspirin, there were 10,000 cases of cancer are preventable, but there are 1,000 people suffering from intestinal bleeding,” he said.
In another study in 2010 also concluded, aspirin reduce the risk of death from all cancers when taken 75 mg per day.
Burn advised to consult your doctor if you want to take aspirin every day. “But if there is a history of cancer of the family, can be considered to take precautions in this way,” he said.
